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THE INFLAMED MIND – A Radical New Approach to Depression with Prof. Ed Bullmore

Professor Ed Bullmore 

Worldwide, depression will be the single biggest cause of disability in the next 20 years. but treatment for it has not changed much in the last three decades. In the world of psychiatry, time has apparently stood still… until now.

This week, Rebecca and Sandie talk to world expert in neuroscience and mental health, Professor Edward Bullmore whose game changing bestseller… The Inflamed Mind: A Radical New Approach to Depressionreveals the breakthrough new science on the link between depression and inflammation of the body and brain.

ED BULLMORE MB PhD FRCP FRCPsych FMedSci trained in medicine at the University of Oxford and St Bartholomew’s Hospital, London; then in psychiatry at the Bethlem Royal & Maudsley Hospital, London. He moved to Cambridge as Professor of Psychiatry in 1999 and was Head of the Department of Psychiatry from 2014-2021. He is currently Director of the Wolfson Brain Imaging Centre, and Deputy Head of the School of Clinical Medicine. He is also an honorary Consultant Psychiatrist and Director of R&D in Cambridgeshire & Peterborough Foundation NHS Trust. From 2005-2019, he worked half-time for GlaxoSmithKline, as VP Experimental Medicine, latterly focusing on immuno-psychiatry, as described in his best-selling book “The Inflamed Mind” (2018). He has published more than 500 scientific papers which have been highly cited (Google h-index 175). He has been elected a Fellow of the Royal College of Physicians, the Royal College of Psychiatrists, and the Academy of Medical Sciences (and as AMS Treasurer since 2018). 

Inflamed Bodies, Depressed Minds

The mysterious connection between the immune system and the brain


We all know depression. It touches every family on the planet. Yet we understand surprisingly little about it.

This dawned on me in an acutely embarrassing way one day in my first few years of raining as a psychiatrist, when I was interviewing a man in the outpatient clinic at the Maudsley Hospital in London. In response to my textbook-drilled questioning, he told me that his mood was low, he wasn’t finding any pleasure in life, he was waking up in the small hours and unable to get back to sleep, he wasn’t eating well and had lost a bit of weight, he was guilty about the past and pessimistic about the future. “I think you’re depressed,” I told him. “I already know that,” the patient told me, patiently. “That’s why I asked my GP to refer me to this clinic. What I want to know is why am I depressed and what can you do about it?”



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